Muramyl dipeptide

CAS No. 53678-77-6

Muramyl dipeptide ( MDP )

Catalog No. M24521 CAS No. 53678-77-6

Muramyl dipeptide is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Muramyl dipeptide
  • Note
    Research use only, not for human use.
  • Brief Description
    Muramyl dipeptide is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln.
  • Description
    Muramyl dipeptide is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide indirectly decreases osteoclast differentiation through a decreased RANKL/OPG ratio. Muramyl dipeptide directly increases osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is an inducer of bone formation through the induction of Runx2 .
  • Synonyms
    MDP
  • Pathway
    MAPK/ERK Signaling
  • Target
    ERK
  • Recptor
    ERK;JNK;p38 MAPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    53678-77-6
  • Formula Weight
    492.5
  • Molecular Formula
    C19H32N4O11
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:98 mg/mL (198.99 mM);Water:98 mg/mL (198.99 mM)
  • SMILES
    CC(N[C@@H]1[C@@H](OC(C(N[C@H](C(N[C@H](CCC(O)=O)C(N)=O)=O)C)=O)C)[C@H](O)[C@@H](CO)O[C@@H]1O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Park OJ, et al. Muramyl Dipeptide, a Shared Structural Motif of Peptidoglycans, Is a Novel Inducer of Bone Formation through Induction of Runx2. J Bone Miner Res. 2017 Jul;32(7):1455-1468.
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